What Is Lipemic Specimen?

What Are Lipemic Samples. Lipemic samples are patient specimens that have a higher fat content in them, so their blood is a little more milky, thicker. Whereas, usually when you spin down whole blood, it will look like this. It has yellow, clear serum or plasma on top of the red cells.

What does it mean when a blood sample is lipemic?

Lipemia is presence of a high concentration of lipids (or fats) in the blood. When donated blood is lipemic it causes the plasma-containing products to have a milky appearance.

What causes a lipemic specimen?
The most common cause of lipemia is nonfasting, with recent ingestion of lipid-containing meal. More severe lipemia results from a disease condition causing hypertriglyceridemia (eg, diabetes, genetic hyperlipidemia) or recent intravenous infusion of a lipid emulsion.

How do you identify a lipemic sample?

Lipemia can be detected visually if the concentration of triglycerides in patient sample is over 3.4 mmol/L (32). In the full blood samples, visual detection is very hard and can be observed at much higher concentration of triglycerides (over 11.3 mmol/L) (32).

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What does lipemia affect?

Lipemia can cause interference in biochemistry results through a variety of mechanisms such as interference in spectrophotometric methods (probably the most common way of interference), heterogeneity of the sample, and volume displacement effect.

Is lipemia bad?

In the clinical laboratory setting, interferences can be a significant source of laboratory errors with potential to cause serious harm for the patient. After hemolysis, lipemia is the most frequent endogenous interference that can influence results of various laboratory methods by several mechanisms. You may also read,

Why is lipemic sample not accepted?

The most common preanalytical cause of lipemia is inadequate time of blood sampling after the meal. In the hospital setting a certain proportion of lipemic samples can’t be avoided, since patients are admitted to the emergency services in various times of the day and various intervals since their last meal. Check the answer of

What is Hemolyzed sample?

Hemolysis is a common occurrence in blood specimens which may compromise laboratory test results. Hemolysis may be due to specimen collection, processing, or transport. … An ordering physician can request that a result be posted regardless of interference by calling the laboratory.

Is MCV affected by lipemia?

Hyperleukocytosis can affect the accuracy of platelet, hemoglobin, and even MCV determinations. Today’s hematology analyzers are quite robust, and most are able to detect unlikely results that “flag” the operator, indicating careful review of the results is needed. Read:

Is it bad to have fat in your blood?

Having high levels of fat in you blood can lead to fatty deposits in the blood vessels in the body, including the coronary arteries (the blood vessels which supply the heart muscle with blood). This leads to the narrowing or hardening of the coronary arteries.

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What causes too much fat in blood?

Most people have high levels of fat in their blood because they eat too much high-fat food. Some people have high fat levels because they have an inherited disorder. High lipid levels may also be caused by medical conditions such as diabetes, hypothyroidism, alcoholism, kidney disease, liver disease and stress.

Can lipemia affect test results?

Lipemia interferes with hematology tests by the following mechanism by light scattering. This affects the following results: Hemoglobin and hemoglobin-related indices: Results in falsely increased absorbance readings of hemoglobin, causing a falsely high measurement.

What are the symptoms of high lipids?

yellowish, fatty bumps or yellow creases on the skin, formed by an accumulation of fatty deposits around tendons and joints (xanthomas

How do you remove fat from your blood?

  1. Aim for a healthy-for-you weight. …
  2. Limit your sugar intake. …
  3. Follow a lower carb diet. …
  4. Eat more fiber. …
  5. Exercise regularly. …
  6. Avoid trans fats. …
  7. Eat fatty fish twice weekly. …
  8. Increase your intake of unsaturated fats.

What are the warning signs of high cholesterol?

  • angina, chest pain.
  • nausea.
  • extreme fatigue.
  • shortness of breath.
  • pain in the neck, jaw, upper abdomen, or back.
  • numbness or coldness in your extremities.